Resorbable Collagen Membrane — Porcine-Derived Bilayer Barrier for GBR & GTR
InterCollagen® Guide is a porcine pericardium-derived resorbable collagen membrane designed for periodontal and oral surgery. Its unique bilayer structure provides dual function — a smooth side that acts as a barrier preventing soft tissue ingrowth, and a rough open-pore side that facilitates bone cell attachment and vascular ingrowth. Dense fibrous architecture delivers 5N suture strength at just 0.13 mm thickness, while the membrane remains highly drapable, easily trimmed, and resorbable within 13 weeks.
Download Product Brochure (PDF)The unique bilayer architecture of InterCollagen® Guide gives each side a specific, complementary role in the guided bone regeneration process.
The smooth, dense side faces the gingival flap and acts as a physical barrier, preventing rapidly proliferating non-osteogenic soft tissue cells from entering the bony defect. This exclusion creates a protected space for bone-forming cells to populate the graft site without competition from fibrous tissue.
The open-pore rough side faces the bone graft or defect, providing a scaffold that facilitates the ingrowth of slow-growing bone-forming cells, nerves, and blood vessels. The multi-scale porous structure supports nutrient exchange, vascularisation, and formation of extracellular matrix (ECM) for dense bone structure development.
InterCollagen® Guide combines mechanical strength, biological function, and clinical ease in a single, versatile resorbable membrane for every guided bone regeneration procedure.
InterCollagen® Guide — Resorbable Collagen Membrane
InterCollagen® Guide can be used alone or in combination with suitable bone augmentation materials for guided bone regeneration (GBR) and guided tissue regeneration (GTR) procedures.
Treatment of fenestration defects around implants or natural teeth — the membrane provides a reliable barrier and protects the underlying graft from soft tissue invasion.
Coverage of dehiscence defects around implants, providing space maintenance and exclusion of non-osteogenic tissue during critical bone healing around exposed implant surfaces.
Covering extraction sockets after tooth removal — used in combination with InterOss® Collagen to seal and protect the socket graft and guide organised bone regeneration.
Following apicoectomy and root resection procedures — the membrane provides a resorbable barrier over the treated area, supporting predictable healing without requiring removal surgery.
Immediate or delayed augmentation around implants in extraction sockets — used to cover bone graft material and maintain the regeneration space for reliable osseointegration.
Coverage of the lateral window in sinus floor elevation procedures — prevents soft tissue ingrowth into the sinus graft from the lateral wall for optimal graft maturation.
InterCollagen® Guide is available in three standard sizes — all trimmable to any smaller shape required. Choose the size that best covers your defect with at least 2–3 mm overlap on all margins.
| SKU | Size | Best For | Notes |
|---|---|---|---|
| ICG1520 | 15 × 20 mm | Single socket, small fenestration, apicoectomy | Ideal starting size for most single-tooth defects |
| ICG2030 | 20 × 30 mm | Multiple sockets, larger ridge defects, sinus window | Most versatile size — trimmable for virtually any indication |
| ICG3040 | 30 × 40 mm | Extensive lateral augmentation, large GBR procedures | Maximum coverage — can be folded or doubled for extra thickness |
Select the appropriate size. Trim to required shape using scissors — in dry or wet conditions. Use templates to minimise waste. Ensure the trimmed membrane will overlap the defect margin by at least 2–3 mm on all sides to prevent lateral tissue ingrowth.
Identify the smooth side (barrier — faces gingiva) and the rough open-pore side (bone-forming — faces graft/bone). For maximum results, place the smooth side towards the gingival flap and the rough side towards the bone graft or defect site.
The membrane can be hydrated in blood or sterile saline solution for improved handling and contouring. Alternatively it can be applied dry — both methods are clinically effective depending on surgical preference and the nature of the defect.
Place the membrane over the graft site, adapting it to the bony walls. The membrane's outstanding drapability allows it to conform to any surface contour and can be easily repositioned if needed before closure.
Additional fixation (pinning, suturing, or screwing) is generally not required due to the membrane's drapability and tear resistance. Ensure tension-free primary closure of the flap over the membrane to prevent premature exposure and bacterial resorption.
Download the complete InterCollagen® Guide brochure — full product specifications, bilayer structure details, suture strength data, size options, placement protocol, SEM microstructure images, and peer-reviewed clinical case studies.
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